About 1 result found for searched term "GNE-900 " (0.177 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M27924 | GNE-900 | Checkpoint |
| GNE-900 is a an ATP-competitive, selective, and orally active ChK1 inhibitor with IC50s of 0.0011, 1.5 µM for ChKl, ChK2, respectively. GNE-900 abrogates the G2-M checkpoint, enhances DNA damage, and induces Apoptosis. gemcitabine and GNE-900 administration shows anti-tumor activity. | ||
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